►个人简介

工作职位：教授，博士生导师，国家高层次青年人才（海外）

办公地址：青岛科技大学CCE大楼1001

工作邮箱：liyantao@qust.edu.cn

招生专业及方向：可招收制药工程、药学、化学工程与技术、化学工程、材料与化工方向的博士、硕士。

个人简介及主要研究领域

教授、博士生导师，主要研究方向为纳米医用复合材料在组织修复、肿瘤治疗、基因递送及疾病传感检测领域的应用。具体包括：纳米生物修复材料在组织修复方面的应用；纳米生物药剂、mRNA疫苗在肿瘤免疫预防与治疗方面的应用；纳米传感材料在疾病因子检测方面的应用。目前在高水平期刊上Nat. Commun.、Adv. Mater.、Angew Chem. Int. Ed.、J. Control. Release、Chem. Eng. J.等上共发表论文60 余篇。主持多项国内外横、纵向科研项目，累积科研经费1500余万元。研究成果不仅被国际知名期刊详细介绍，也受到国内外科技媒体平台邀约，以人物专访形式报道；同时担任青岛市药学会委员、Nano TransMed、PolyChem、Eng. Regen.等期刊编委，以及诸多高水平期刊特邀审稿人。

►主要科研项目

[1]国家自然科学基金（面上项目）：“金属-脂质配位调控mRNA脂质纳米粒的免疫器官靶向与激活机制研究”，（项目编号：22675180），2027.01-2030.12，主持，经费50万元。

[2]国家自然科学基金海外优青项目及省、市、学校配套支持项目：新型多功能纳米复合材料的制备和性能调控，2023-2028，主持，经费700万元。

►代表性论文与著作

[1]Yu Han, Guohua Ma, Kai Zhang, Runcai Xu, Ning Xin, Jingtong An, Ning Wang, andYantao Li*,“Zn(II)-adjuvanted imidazole-based lipid nanoparticles for potent spleen-targeted mRNA delivery and enhanced immune activation”,J. Control. Release2026, 392, 114742.(一区Top, IF=10.5)

[2]Yu Han, Xintao Gao, Jiqing Dong, Mingquan Jian, Ning Xin, Xiangyan Chen, Zhibo Li,* andYantao Li*, “Zn-LNP coordinated nanoassembly-based mRNA vaccines for synergistic spleen-targeted delivery and potent tumor suppression via immunoprophylaxis and immunotherapy”,Chem. Eng. J.2026, 529, 173282. (一区Top, IF=13.3)

[3]Junyao Li, Xiaochen Wu, Xintao Gao, Jingtong An, Qishan Xu, Xiangyan Chen,* andYantao Li*, “Bioactive nanoreactor-enhanced injectable polysaccharide hydrogels for tissue regeneration and scar suppression via multifactorial regulation in infected burn wounds”,Chem. Eng. J.2026, 530, 173688. (一区Top, IF=13.3)

[4]Qizhen Wang, Jia Xu, Yuehao Xu, Xiangyan Chen, Xintao Gao, Junyao Li, Qishan Xu, Fusheng Liu,* and Yantao Li*,“Hierarchical Integration of MOF-Based Nanoplatforms with Electrospun Nanofiber Scaffolds for Spatiotemporally Sustained Diabetic Wound Healing”,Adv. Healthcare Mater.2026, 15, e03699. （一区Top, IF=10.8）

[5]Qishan Xu, Mingquan Jiang, Xiangyan Chen, Xintao Gao, Yan Lei, Zhibo Li,* andYantao Li*, “Effective nanostructure regulation of hierarchically porous MOFs-based nanoplatforms for cascade enhanced tumor-specific therapy”,Chem. Eng. J.2026, 536, 176082. (一区Top, IF=13.3)

[6]Xuetong Ji, Junyao Li, Xintao Gao, Jiqing Dong, Linlin Ma, Yu Han,* Xiangyan Chen,* andYantao Li*, “A Barnacle-Inspired Hydrogel Enables External-Internal Synergistic Modulation of NF-κB/Nrf2 Signaling for Diabetic Wound Healing”,Chem. Eng. J.2026, 539, 177272. (一区Top, IF=13.3)

[7]Yu Han, Kai Zhang, Ning Xin, Xintao Gao, Guohua Ma, Jingtong An, and Yantao Li*,“Zn-coordinated lipid nanoparticles synergistically enhance spleen-targeting delivery and elicit CD8+T cell-mediated cancer immunotherapy”,J. Colloid Interface Sci.2026, 702, 139025.(一区Top, IF=9.7)

[8]Yantao Li, Jiaming Liu, Zuochao Wang, Jun Jin, Yaling Liu,* Chunying Chen,* and Zhiyong Tang*, “Optimizing Energy Transfer in Nanostructures Enables in vivo Cancer Lesion Tracking via Near-Infrared Excited Hypoxia Imaging”,Adv. Mater.2020, 32, 1907718. (一区Top, IF=28.9)

[9]Yantao Li, Kai Zhang, Porun Liu, Mo Chen, Yulin Zhong, Qingsong Ye,Ming Q. Wei,* Huijun Zhao,* and Zhiyong Tang*, “Encapsulation of Plasmid DNA by Nanoscale Metal-Organic Frameworks for Efficient Gene Transportation and Expression”,Adv. Mater.2019, 31, 1901570. (一区Top, IF=28.9)

[10]Yantao Li, Jinglong Tang, Liangcan He, Yong Liu, Yaling Liu,* Chunying Chen,* and Zhiyong Tang*, “Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging”,Adv. Mater.2015, 27, 4075. (一区Top, IF=28.9, Highly cited paper)

欢迎具备材料合成与制备化学、生命医学、理论模拟、机器学习以及相关交叉领域研究背景的同学报考本实验室的研究生，同时招聘相关博士后、工作人员等。