个人简介:欧阳旋慧
工作职位:药物化学教研室,教授,泰山学者青年专家,博士生导师
办公地址:青岛科技大学四方校区CCF楼317室
工作邮箱:xuanhuiouyang@163.com
2018年获湖南大学博士学位。主要从事有机合成化学、药物合成、精细化工和催化化学等方面研究。开展科学研究工作以来,以第一作者或通讯作者身份在Sci. Adv., Angew. Chem Int. Ed., Org. Lett.和Org. Chem. Front.等期刊上发表SCI学术论文近41篇,申请(含授权)发明专利11项, H-Index为30, 他引2700余次。同时担任Org. Lett.、Org. Chem. Front., J. Org. Chem.、Adv. Synth. Catal.等期刊审稿人。主持国家自然科学基金面上等3项,山东省泰山学者青年专家人才项目、江西省杰出青年基金、江西省主要学科学术和技术带头人培养计划-青年人才等省部级项目6项。指导研究生和本科生多次获国家奖学金和省政府奖学金和校优秀本科毕业论文。2019年获得江西省科学技术奖自然科学奖一等奖一项(排名第三)。
教学情况:
药物化学:32课时,本科生。
代表性论文:
1) Xuan-Hui Ouyang,+ Yang Li,+ Ren-Jie Song*, Ming Hu, Shenlian Luo and Jin-Heng Li* Intermolecular dialkylation of alkenes with two distinct C(sp(3))-H bonds enabled by synergistic photoredox catalysis and iron catalysis. Science Advances 2019, 5, eaav9839.
2) Xuan-Hui Ouyang+, Ren-Jie Song+, Ming Hu, Yuan Yang and Jin-Heng Li* Silver-Mediated Intermolecular 1,2-Alkylarylation of Styrenes with a-Carbonyl Alkyl Bromides and Indoles, Angew. Chem. Int. Ed. 2016, 55, 3187-3191.
3) Wan-Ting Li, Zhi-Xia Zhang, Jing Huang, Hui-Min Jiang, Zhen-Wei Luo, Jin-Heng Li,* and Xuan-Hui Ouyang* Photochemical Divergent Ring-Closing Metathesis of 1,7-Enynes: Efficient Synthesis of Spirocyclic Quinolin-2-ones, Org. Lett., 2024, 26, 6664−6669.
4) Liang Zeng,† Hua-Zhan Ren,† Gui-Fen Lv, Xuan-Hui Ouyang,* De-Liang He, and Jin-Heng Li* Electroreductive Remote Benzylic C(sp3)−H Arylation of Aliphatic Ethers Using Cyanoarenes for the Synthesis of α‑(Hetero)aryl Ethers, Org. Lett. 2024, 26, 2440−2444.
5) Liang Zeng, Yin Zhang, Ming Hu,* De-Liang He, Xuan-Hui Ouyang,* and Jin-Heng Li*, Divergent Synthesis of (E)- and (Z)‑Alkenones via Photoredox C(sp3)−H Alkenylation−Dehydrogenation of o‑Iodoarylalkanols with Alkynes, Org. Lett. 2024, 26, 10096−10101.
6) Liang-Feng Yang, Zhi-Qiang Xiong, Xuan-Hui Ouyang,* Qiu-An Wang, and Jin-Heng Li* Cobalt-Promoted Photoredox 1,2-Amidoamination of Alkenes with N‑Sulfonamidopyridin-1-ium Salts and Free Amines, Org. Lett. 2024, 26, 1667−1671.
7) Han-Qing Zhao,∇ Wan-Ting Li,∇ Yong Yao, Yi-Lin Zhao, and Xuan-Hui Ouyang* Iron-Catalyzed Perfluoroalkylarylation of Styrenes with Arenes and Alkyl Iodides Enabled by Halogen Atom Transfer, Org. Lett., 2024, 26, 10183−10188.
8) Tian-Bao Zhang, Fang Wang, Jun-Yao Ouyang, Zhen-Wei Luo, Jing-Hao Qin, Jin-Heng Li, and Xuan-Hui Ouyang*Aryldiazonium-Salt-Triggered Carboxylative Azotization of Pyrroles or Indoles with Polyhalomethanes via Halogen-Atom Transfer (XAT), Org. Lett. 2024, 26, 461−466.
9) Yi-Lin Zhao, Yong Yao, Wan-Ting Li, Jing-Hao Qin, Qing Sun, Jin-Heng Li* and Xuan-Hui Ouyang* Copper-Catalyzed Functionlization/Transformation of Styrenes with Polyhaloalkanes and Arenes Enables Heteroarene-Containing gem-Dihaloalkenes Synthesis. Org. Chem. Front., 2023, 10, 4809-4815.
10) Jun-Yao Ouyang, Fang-Fang Shen, Han-Qing Zhao, Jia-Jie Chen, Zhu-Dong Wen, Hui-Min Jiang, Jing-Hao Qin, Qing Sun,* Jin-Heng Li,* Xuan-Hui Ouyang* Aryldiazonium Salt-Triggered [2 + 2 + 1] Heteroannulation of Indoles by an Arylhydrazone Radical-Relayed 1,5-Hydrogen Atom Transfer. Org. Lett. 2023, 25, 6549-6554.
11) Tian-Bao Zhang, Yong Yao, Jing-Hao Qin, Qing Sun, Aimin Li, Qing He,* Jin-Heng Li* and Xuan-Hui Ouyang,* Polyhaloalkanes as the C1 Source: Radical-Mediated Migratory Carbonylation of Alkenes with Polyhaloalkanes toward α,β-Unsaturated Carbonyls. Org. Chem. Front., 2023, 10, 4670-4678.
12) Liang Zeng, Jing-Hao Qin, Gui-Fen Lv, Min Hu,* Qing Sun,* Xuan-Hui Ouyang* De-Liang He,* and Jin-Heng Li* Electrophotocatalytic Reductive 1,2-Diarylation of Alkenes with Aryl Halides and Cyanoaromatics. Chin. J. Chem. 2023, 41, 1921-1930.
13) Hui-Min Jiang, Jing-Hao Qin, Qing Sun, Dong Zhang, Jin-Peng Jiang, Xuan-Hui Ouyang,* Ren-Jie Song,* Jin-Heng Li* Copper-Promoted Cross Coupling of Nitroarenes with 4-Alkyl-1,4-dihydropyridines using a Peroxide-Driven Radical Reductive Strategy. Org. Chem. Front., 2022, 9, 4070-4077.
14) Bin Wei, Jing-Hao Qin, Yong-Zheng Yang, Ye-Xiang Xie, Xuan-Hui Ouyang,* Ren-Jie Song,* Electrochemical radical C(sp3)-H arylation of xanthenes with electron-rich arenes, Org. Chem. Front., 2022, 9, 816-821.
15) Jing Huang, Yun-Yan Liang, Xuan-Hui Ouyang,* Yu-Ting Xiao, Jing-Hao Qin, Ren-Jie Song,* Jin-Heng Li* Three-component photoredox 1,2-alkylamination of styrenes with alkanes and nitrogen nucleophiles via C(sp3)-H bond cleavage, Org. Chem. Front. 2021, 8, 7009-7014.
16) Shiqi Tong, Kewei Li, Xuan-Hui Ouyang,* Ren-Jie Song,* Jin-Heng Li* Recent advances in the radical-mediated decyanative alkylation of cyano(hetero)arene Green Synthesis and Catalysis 2021, 2, 145-155.
17) Yun-Yan Liang, Jing Huang, Xuan-Hui Ouyang,* Jing-Hao Qin, Ren-Jie Song, Jin-Heng Li* Radical-Mediated Alkoxypolyhaloalkylation of Styrenes with Polyhaloalkanes and Alcohols via C(sp3)-H Bond Cleavage, Chem. Commun. 2021, 57, 3684-3687.
18) Zi-Liang Tang, Xuan-Hui Ouyang,* Ren-Jie Song, and Jin-Heng Li* Decarboxylative C(sp3)−N Cross-Coupling of Diacyl Peroxides with Nitrogen Nucleophiles Org. Lett. 2021, 23, 1000-1004.
19) Xia Wang,+ Ya-Fei Han,+ Xuan-Hui Ouyang*, Ren-Jie Song*, Jin-Heng Li*, The photoredox alkylarylation of styrenes with alkyl N-hydroxyphthalimide esters and arenes involving C–H functionalization, Chem. Commun. 2019, 55, 14637-14640.
20) Xuan-Hui Ouyang, Yang Li, Ren-Jie Song,* and Jin-Heng Li* Alkylamination of Styrenes with Alkyl N‑Hydroxyphthalimide Esters and Amines by B(C6H5)3-Facilitated Photoredox Catalysis Org. Lett. 2018, 20, 6659-6662.