►个人简介

工作职位：特聘副教授

办公地址：CCF317

工作邮箱：dushaoqing@qust.edu.cn

招生专业及方向：药学、制药工程

个人简介及主要研究领域

主要从事药物分子设计与合成，靶向新冠核衣壳蛋白、HIV-1逆转录酶、鱼尼丁受体、烟碱型乙酰胆碱受体、琥珀酸脱氢酶等开展药物创制。在国内外核心期刊发表以第一作者/通讯作者发表论文20余篇，包括Signal Transduct. Tar. Ther.、Drug Resist. Update.、Acta Pharm. Sin. B、J. Med. Chem.、Chinese Chem. Lett.、Eur. J. Med. Chem.、J. Agric. Food Chem.等。主持国家自然科学基金2项。

►主要教科研项目

[1]国家自然科学基金（青年科学基金项目）：基于结构的邻氨基苯甲酰胺类化合物的设计，合成和杀虫活性研究，（项目编号：22208191），2023/01-2025/12，主持，经费30万元。

►代表性论文与著作

[1]Du Shaoqing, Hu Xueping, Luis Menendez-Arias, Peng Zhan, Xinyong Liu.Target-based drug design strategies to overcome resistance to antiviral agents: opportunities and challenges.Drug Resist. Update.2024, 73, 101053.(SCI 1区 Top, IF:21.99).

[2]Shaoqing Du, Qingjie Yang, Yan Lin, Li Cui, and Xueping Hu.Design, synthesis, insecticidal activities, and structure−activity relationship of phenylpyrazole derivatives incorporating 1,2,4-oxadiazole moiety.J. Agric. Food Chem.2025, 73, 23916−23924.(SCI 1区 Top, IF:6.70).

[3]Du Shaoqing, Xueping Hu, Ping Li, Shujing Xu, Meehyein Kim, Xinyong Liu, Peng Zhan.Antiviral drug discovery and development: Challenges and future directions.Signal Transduct. Tar. Ther.2026, 11, 69.(SCI 1区 Top, IF:81.19).

[4]Jiaojiao Dai, Xiangyi Jiang, Heng Gao, Boshi Huang, Erik De Clercq, Christophe Pannecouque,Shaoqing Du*, Xinyong Liu*, Peng Zhan*.Discovery of novel fused-heterocycle-bearing diarypyrimidine derivatives as HIV-1 potent NNRTIs targeting tolerant region I for enhanced antiviral activity and resistance profile.Eur. J. Med. Chem.2025, 281, 117033.(SCI 1区 Top, IF:6.70).

[5]Du Shaoqing, Xinyong Liu, Hu Xueping, Peng Zhan.Viral protein dimerization quality control: A design strategy for a potential viral inhibitor.J. Med. Chem.2024, 67, 16951–16966.(SCI 1区 Top, IF:7.30).

►授权专利

[1] 钱旭红，邵旭升，杜少卿等. 含1,2,4-恶二唑的酰胺类化合物及其盐的制备和用途[P]. CN 115340536 B.2024/12/10. (‌发明专利)

[2] 钱旭红，邵旭升，杜少卿等. 悉尼酮与悉尼酮亚胺类化合物及其制备方法和用途[P]. CN 111057024 B.2025/02/07. (‌发明专利)

[3] 钱旭红，邵旭升，杜少卿等. 一种含羰基化合物及其制备方法和用[P].CN 113024379 B.2025/05/27. (‌发明专利)