►个人简介

工作职位：药物制剂教研室，特聘副教授

办公地址：青岛科技大学CCF432

工作邮箱：dushaoqing@qust.edu.cn

2014年获山东农业大学植物保护学士学位，2016年获中国农业大学农药学硕士学位，2021年获华东理工大学农药学博士学位，2022年至2025年于山东大学药学院工作。目前在青岛科技大学化工学院工作。

主要从事

新药设计与合成研究。主持国家自然科学基金一项。

代表性研究成果发表于Signal Transduct. Tar. Ther.（1篇，IF=52）、Drug Resist. Update.（1篇，IF=24）、Acta Pharm. Sin. B（1篇，IF=14.8）、J. Med. Chem.（3篇，IF=6.8）、Chinese Chem. Lett. （1篇，IF=9.4）、 Eur. J. Med. Chem.（1篇，IF=6）、Drug Discov. Today（3篇，IF=7.4）、J. Agric. Food Chem.（3篇，IF=6.1）等国内外学术期刊以第一作者或通讯作者发表学术论文20余篇，授权发明专利4项。主讲本科专业课程《精细有机合成原理及工艺》。

►教学情况

►本科生课程

[1] 精细有机合成原理及工艺：40课时，约120人。

►研究生招生

团队拥有气质联用、高效液相、超临界色谱和手套箱等仪器，科研经费和实验条件充足，课题组氛围融洽，热情欢迎新同学的加入！

►论文、专著与专利

1、论文

[1] Du Shaoqing¹, Hu Xueping¹, Luis Menendez-Arias*, Peng Zhan*, Xinyong Liu*. Target-based drug design strategies to overcome resistance to antiviral agents: opportunities and challenges. Drug Resist. Update. 2024, 73, 101053.

[2] Jiaojiao Dai, Xiangyi Jiang, Heng Gao, Boshi Huang, Erik De Clercq, Christophe Pannecouque, Shaoqing Du*, Xinyong Liu*, Peng Zhan*. Discovery of novel fused-heterocycle-bearing diarypyrimidine derivatives as HIV-1 potent NNRTIs targeting tolerant region I for enhanced antiviral activity and resistance profile. Eur. J. Med. Chem. 2025, 281, 117033.

[3] Du Shaoqing, Xinyong Liu*, Hu Xueping*, Peng Zhan*. Viral protein dimerization quality control: A design strategy for a potential viral inhibitor. J. Med. Chem. 2024, 67, 16951–16966.

[4] Jiaojiao Dai, Xiangyi Jiang, Edeildo Ferreira da Silva-Júnior, Shaoqing Du*, Xinyong Liu*, Peng Zhan*. Recent advances in the molecular design and applications of viral RNA-targeting antiviral modalities. Drug Discov. Today. 2024, 29, 104074.

[5] Du Shaoqing¹, Hu Xueping¹, Xinyong Liu*, Peng Zhan*. Revolutionizing viral disease treatment: Phase separation and lysosome/exosome targeting as new areas and new paradigms for antiviral drug research. Drug Discov. Today. 2024, 29, 103888.

[6] Du Shaoqing, Hu Xue ping^*. Comprehensive overview of diamide derivatives acting as ryanodine receptor activators. J. Agric. Food Chem. 2023, 71(8), 3620-3638.

[7] Shaoqing Du, Qingjie Yang, Yan Lin, Li Cui,* and Xueping Hu^*.Design, synthesis, insecticidal activities, and structure−activity relationship of phenylpyrazole derivatives incorporating 1,2,4-oxadiazole moiety. J. Agric. Food Chem. 2025, 73, 23916-23924.

[8] Du Shaoqing, Hu Xueping*, Craig W. Lindsley*, Peng Zhan*. New applications of sulfonyl fluorides: A microcosm of the deep integration of chemistry and biology in drug design. J. Med. Chem. 2024, 67, 16925–16927.

[9] Du Shaoqing, Xinyong Liu*, Hu Xueping*, Peng Zhan*. Targeting novel sites represents an effective strategy for combating drug resistance. Chinese Chem. Lett. 2025, 36, 110378.

[10] Du Shaoqing, Hu Xueping*, Craig W. Lindsley*, Peng Zhan*. Medicinal chemistry education: Emphasize fundamentals and skillfully integrate knowledge. J. Med. Chem. 2024, 67, 19929–19931.

[11] Du Shaoqing¹, Hu Xueping¹, Xinyong Liu*, Peng Zhan*. The development of antiviral drug discovery. Acta Pharm. Sin. B 2025, 15, 2801-2804.

[12] Du Shaoqing, Luis Menéndez-Arias*, Hu Xueping*, Peng Zhan*. Therapeutic approaches to addressing drug resistance by targeting membranes and associated structures. Drug Discov. Today 2025, 30, 104526.

[13] Du Shaoqing¹, Xueping Hu¹, Ping Li, Shujing Xu, Meehyein Kim*, Xinyong Liu*, Peng Zhan*. Antiviral drug discovery and development: Challenges and future directions. Signal Transduct. Tar. Ther. 2026, 11, 69.

2、专著

[1] 中国农药研究与应用全书 农药创新（参与）

3、授权专利

[1] 钱旭红，邵旭升，杜少卿等。含1,2,4-恶二唑的酰胺类化合物及其盐的制备和用途. (CN 115340536 B)

[2] 段红霞，杜少卿等。含茉莉酸基团的(反)-β-法尼烯类似物及其制备方法与应用. (CN 106117064 B)

[3] 钱旭红，邵旭升，杜少卿等。悉尼酮与悉尼酮亚胺类化合物及其制备方法和用途. (CN 111057024 B)

[4] 钱旭红，邵旭升，杜少卿等。一种含羰基化合物及其制备方法和用途. (CN 113024379 B)

►承担的科研项目

1、纵向项目

[1] 国家自然科学基金青年科学基金项目，基于结构的邻氨基苯甲酰胺类化合物的设计，合成和杀虫活性研究，22208191，30万元，2023/01-2025/12，主持，已结题。